Oxcarbazepine is having poor water solubility and suffering with dissolution rate limited bioavailability. It belongs to class II category under biopharmaceutical classification and needs to improvement of dissolution. Various approaches for improving dissolution rate were reported previously but there is no reports regarding the impact of pharmaceutical factors on the dissolution rate of Oxacarbazepine. The present study is representing the data regarding the effect of various excipients (diluents, superdisintegrants, and lubricants) and method of preparation on the dissolution rate of Oxacarbazepine. oxcarbazepine tablets composed with the diluent (mannitol), super disintegrant (crospovidone), lubricant (magnesium stearate) and the glidant (talc) and compressed by employing direct compression technique was found to comply all the official quality control tests and produced more drug release among the other formulations and offered the similarity in dissolution profiles, as the value of similarity factor value is more than 50.
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